Screening for polymorphs is crucial during drug development, since the crystal form of the active pharmaceutical ingredient (API) directly correlates with its pharmacokinetic properties. The ability to image and detect spatially variable changes in the drug substance becomes important in determining the drug products efficacy and performance and has significant impact on intellectual property rights. Understanding why these polymorphs develop can ultimately help drug developers and formulators to engineer a process that will ensure stability of the right API.
This webinar is designed for scientists working in the area of polymorph analysis in pharmaceutical products and will discuss the benefit of using Raman microscopy and chemical imaging for in vitrocharacterization of polymorphs.
Highlighted Topics Covered:
- The benefit of using Raman microscopy and chemical imaging for in vitro characterization of polymorphs
- Utilizing chemical imaging to understand the molecular state of the polymorph
- Utilizing chemical imaging to understand the transformation properties of the polymorph