Proactive Versus Reactive Testing For Glass Delamination in Pharmaceuticals

Authors & Contributors

Glass delamination, which is a reaction from a form of glass corrosion, are small, thin, glass fragments, termed “glass lamellae”, which are shed from the interior portion of glass containers and vials. USP 1660 describes a methodology for evaluating various glass vials under simulated conditions. The results from these types of approaches can be difficult to translate to the issue of compatibility of a specific drug product with specific vial types in real-life scenarios.