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Identification of Foreign Particulate Matter Using Automated Raman & Automated SEM-EDS

Authors & ContributorsRebekah ByrneDavid ExlineEmily Landsperger

March 27, 2015

Foreign particulate matter in drug products is a common problem in the pharmaceutical industry that can have major impacts on pharmaceutical companies, from both financial and safety aspects. While manual particulate characterization is best suited for many investigations, automated Raman and automated Scanning Electron Microscopy/Electron Dispersive Spectroscopy (SEM-EDS) analyses can offer additional insight and investigative solutions to contamination issues, including foreign particulate matter. Automated Raman and automated SEM-EDS analyses offer the ability to establish the size and chemical composition of hundreds of particles in a sample, whether the chemical makeup is metallic, organic or inorganic […]

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