• RT @aptar: A successful @CPhIWW Worldwide 2019 is behind us. #AptarPharma would like to thank everyone for coming to meet us! See you again…

Call us Today!
+1 (724) 443-1900

2017 RDD Europe: Advancing the Determination of In Vitro Similarity in Tiotropium Formulations for Inhalation

Authors & ContributorsDavid Exline

May 09, 2017

Three dry powder formulations of tiotropium bromide were manufactured for in vitro comparison to Spiriva® HandiHaler®. In this study, aerodynamic particle size distribution (APSD) characterization techniques that simulate patient conditions coupled with particle chemistry, morphology and size analysis were used to determine differences in the tiotropium bromide formulations. The objective of this study was to determine the comparability of the formulations using traditional and novel in vitro methods.

Download Resource