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2017 AAPS Annual Conference: Two-Sample T-Test for the Determination of Optimal API Sample Size for Particle Population Studies

Authors & ContributorsDavid Exline

December 12, 2017

A common scientific question, specifically in the area of Active Pharmaceutical Ingredient (API) particle size distribution, is the optimal sample size for analyzing a particle population. Many times, the answer is merely a suggestion or preference. However, by understanding simple statistical ideas, we can provide a basis for the answer to this question.

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