2017 AAPS Annual Conference: Two-Sample T-Test for the Determination of Optimal API Sample Size for Particle Population Studies

Authors & Contributors

A common scientific question, specifically in the area of Active Pharmaceutical Ingredient (API) particle size distribution, is the optimal sample size for analyzing a particle population. Many times, the answer is merely a suggestion or preference. However, by understanding simple statistical ideas, we can provide a basis for the answer to this question.