Raman Chemical Imaging: Polymorph Discrimination
Original Event Date: Thursday, Aug. 23, 2012
Time: 1 p.m. EDT
Duration: 1 hour
Presenter: Oksana Olkhovyk, Ph.D., Senior Scientist, Gateway Analytical
Host: Brittney Higgs, Graphics & Web Manager, Gateway Analytical
Highlighted Topics Covered:
- The benefit of using Raman microscopy and chemical imaging for in vitro characterization of polymorphs
- Utilizing chemical imaging to understand the molecular state of the polymorph
- Utilizing chemical imaging to understand the transformation properties of the polymorph
Screening for polymorphs is crucial during drug development, since the crystal form of the active pharmaceutical ingredient (API) directly correlates with its pharmacokinetic properties. The ability to image and detect spatially variable changes in the drug substance becomes important in determining the drug products efficacy and performance and has significant impact on intellectual property rights. Understanding why these polymorphs develop can ultimately help drug developers and formulators to engineer a process that will ensure stability of the right API.
This webinar is designed for scientists working in the area of polymorph evaluation in pharmaceutical products and will discuss the benefit of using Raman microscopy and chemical imaging for in vitro characterization of polymorphs.
Dr. Oksana Olkhovyk
Oksana Olkhovyk, Ph.D., Senior Scientist
Gateway Analytical
Dr. Oksana Olkhovyk has more than 10 years of chemical imaging experience in the pharmaceutical and materials science industries. Dr. Olkhovyk applies her expertise in physical chemistry and materials science to advance development of products and processes using chemical imaging techniques. Dr. Olkhovyk specializes in numerous optical spectroscopy and microscopy techniques; innovative applications of chemical imaging, materials synthesis and characterization; and surface chemistry.
As a Senior Scientist at Gateway Analytical, Dr. Olkhovyk develops analytical methods for chemical and materials analysis using Raman, NIR and fluorescence spectroscopy and imaging technology to support key commercial projects.
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