Articles & Publications

Discover the latest articles and publications pertaining to Gateway Analytical.

Identification of Foreign Particulate Matter Using Automated Raman & Automated SEM-EDS

Identification of Foreign Particulate Matter Using Automated Raman & Automated SEM-EDS

Foreign particulate matter in drug products is a common problem in the pharmaceutical industry that can have major impacts on pharmaceutical companies, from both financial and safety aspects. […]

A Forensic Approach to Particulate Contamination in Inhalable Drug Products

A Forensic Approach to Particulate Contamination in Inhalable Drug Products

Contamination in drug products is a common problem in the pharmaceutical industry that can have major impacts on pharmaceutical companies, from both financial and safety aspects. Inhalable drug products are unique with regards to the affects of contamination, due to enduse design.

Using Raman Chemical Imaging to Analyze Inhaled Combination Therapies

Using Raman Chemical Imaging to Analyze Inhaled Combination Therapies

Since the approval of the Seretide (Advair) fluticasone/salmeterol dry powder inhaler in 1999, inhaled therapies that combine a bronchodilator, often a longacting beta agonist (LABA), with a maintenance drug, usually an inhaled corticosteroid (ICS), have taken over a large portion of the asthma and COPD markets. And, increasingly, a long-acting muscarinic antagonist (LAMA) is being added to LABA/ICS formulations to create triple therapy combinations.

Analysis of Multi-Component Engineered Particles for Inhalation by Raman Chemical Imaging

Analysis of Multi-Component Engineered Particles for Inhalation by Raman Chemical Imaging

One of the most promising trends in inhaled therapies over the past few years is the creation of particles that contain multiple active ingredients. Some studies have suggested that two, or even three, APIs deposited in the same location in the lung may have a synergistic effect.